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장경순 교수

Kyoung-Soon JANG

INFO

  • 소속캠퍼스한국기초과학지원연구원
  • 전공 생물분석과학
  • 연락처043-240-5196
  • 출신전공생물화학공학
  • 학위박사
  • 최종출신대학서울대학교
  • 이메일

연구분야

초고분해능 질량분석기를 활용한 단백체 및 환경유기대사체

Ultra-high resolution mass spectrometry-based proteomics and environmental metabolomics

대표연구실적

-  Choi, J.H., Ryu, J., Jeon, S., Seo, J., Yang, Y.H., Pack, S.P., Choung, S., Jang, K.S. “In-depth compositional analysis of water-soluble and ?insoluble organic substances in fine (PM2.5) airborne particles using ultra-high-resolution 15T FT-ICR MS and GCxGC-TOFMS” Environmental Pollution (2017) (DOI: 10.1016/j.envpol.2017.02.058) -  Cha, J.Y., Kim, T.W., Choi, J.H., Jang, K.S., Khaleda, L., Kim, W.Y., Jeon, J.R. “Fungal laccase-catalyzed oxidation of naturally occurring phenols for enhanced germination and salt tolerance of Arabidopsis thaliana: a green route for synthesizing humic-like fertilizers” Journal of Agricultural and Food Chemistry (2017) -  Jang, K.S., Park, M., Lee, J.Y., Kim, J.S. “Mass spectrometric identification of phenol-soluble modulins in the ATCC® 43300 standard strain of methicillin-resistant Staphylococcus aureus harboring two distinct phenotypes” European Journal of Clinical Microbiology & Infectious Diseases (2017)

논문(최근 5년)

-  A MALDI-MS-based quantitative analytical method for endogenous estrone in human breast cancer cells[Scientific Reports,2016-04-19] -  Linear correlation of aliphatic diamines to response factors by number of carbons in GC-MS[JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY,2015-06-11] -  Development of semi-synthetic microbial consortia of Streptomyces coelicolor for increased production of biodiesel (fatty acid methyl esters)[ FUEL,2015-06-30] -  A cationic cysteine-hydrazide as an enrichment tool for the mass spectrometric characterization of bacterial free oligosaccharides[ ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2015-06-23] -  Incorporation of unnatural amino acids in response to the AGG codon[ACS chemical biology,2015-05-06] -  Differential immune-stimulatory effects of LTAs from different lactic acid bacteria via MAPK signaling pathway in RAW 264.7 cells[ IMMUNOBIOLOGY,2014-11-13] -  An on-line platform for the analysis of permethylated oligosaccharides using capillary liquid chromatography-electrospray ionization-tandem mass spectrometry[ JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2014-01-01] -  Comprehensive proteomic profiling of outer membrane vesicles from Campylobacter jejuni[JOURNAL OF PROTEOMICS,2013-12-29] -  Protein engineering of ?2,3/2,6-sialyltransferase to improve the yield and productivity of in vitro sialyllactose synthesis[ GLYCOBIOLOGY,2013-10-13] -  The Xeno-glycomics database (XDB): a relational database of qualitative and quantitative pig glycome repertoire[ BIOINFORMATICS,2013-09-06] -  The sweets standing at the borderline between allo- and xenotransplantation[ XENOTRANSPLANTATION,2013-02-28]

특허(최근 5년)

-  Cysteine hydrazide nicotinamide for glycomics and glycoproteomics[2014-03-13] -  Novel N-acetylglucosamine-2-epimerase and method for producing CMP-NeuAc using the same[2014-10-07]

연구과제 수행 실적

말초신경병증 단백체분석 세팔로스포린계 항생제에 대한 다제내성균 내성 고속진단 플랫폼 개발 질량분석기반 천연물 조각이온 검색엔진 범용 시스템 개발 초고분해능 질량분석기를 활용한 기후냉각물질(미세먼지) 화학특성 분석 프로폴리스 지표성분 정밀분석을 통한 원산지 판별 기술 개발