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장경순 교수

Kyoung-Soon JANG

INFO

  • 소속캠퍼스한국기초과학지원연구원
  • 전공 생물분석과학
  • 연락처043-240-5196
  • 출신전공생물화학공학
  • 학위박사
  • 최종출신대학서울대학교
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연구분야

초고분해능 질량분석기를 활용한 단백체 및 환경유기대사체

Ultra-high resolution mass spectrometry-based proteomics and environmental metabolomics

대표연구실적

-  Park, H.G.*, Jang, K.S.*, Park, H.M., Song, W.S., Jeong, Y.Y., Ahn, D.H., Kim, S.M., Yang, Y.H., Kim, Y.G. (*co-first authors) “MALDI-TOF MS-based total serum protein fingerprinting for liver cancer diagnosis” Analyst (2019) 144: 2231-8. -  Jang, K.S.*, Park, M., Lee, J.Y., Kim, J.S.* (*co-corresponding authors) “Mass spectrometric identification of phenol-soluble modulins in the ATCC® 43300 standard strain of methicillin-resistant Staphylococcus aureus harboring two distinct phenotypes” European Journal of Clinical Microbiology & Infectious Diseases (2017) 36: 1151-7. -  Choi, J.H., Ryu, J., Jeon, S., Seo, J., Yang, Y.H., Pack, S.P., Choung, S., Jang, K.S. “In-depth compositional analysis of water-soluble and insoluble organic substances in fine (PM2.5) airborne particles using ultra-high-resolution 15T FT-ICR MS and GCxGC-TOFMS” Environmental Pollution (2017) 225:329-37.

논문(최근 5년)

-  A MALDI-MS-based quantitative analytical method for endogenous estrone in human breast cancer cells[Scientific Reports,2016-04-19] -  Linear correlation of aliphatic diamines to response factors by number of carbons in GC-MS[JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY,2015-06-11] -  Development of semi-synthetic microbial consortia of Streptomyces coelicolor for increased production of biodiesel (fatty acid methyl esters)[ FUEL,2015-06-30] -  A cationic cysteine-hydrazide as an enrichment tool for the mass spectrometric characterization of bacterial free oligosaccharides[ ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2015-06-23] -  Incorporation of unnatural amino acids in response to the AGG codon[ACS chemical biology,2015-05-06] -  Differential immune-stimulatory effects of LTAs from different lactic acid bacteria via MAPK signaling pathway in RAW 264.7 cells[ IMMUNOBIOLOGY,2014-11-13] -  Fungal laccase-catalyzed oxidation of naturally occurring phenols for enhanced germination and salt tolerance of Arabidopsis thaliana: a green route for synthesizing humic-like fertilizers[JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2017-01-23] -  Chemical structure of the lipid A component of Pseudomonas sp. Strain PAMC 28618 from thawing permafrost in relation to pathogenicity[SCIENTIFIC REPORTS,2017-05-19] -  In-depth compositional analysis of water-soluble and -insoluble organic substances in fine (PM2.5) airborne particles using ultra-high-resolution 15T FT-ICR MS and GCxGC-TOFMS[ENVIRONMENTAL POLLUTION,2017-03-06] -  Mass spectrometric identification of phenol-soluble modulins in the ATCC 43300 standard strain of methicillin-resistant Staphylococcus aureus harboring two distinct phenotypes[EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES,2017-01-14] -  Chemical characterization of dissolved organic matter in moist acidic tussock tundra soil using ultra-high resolution FT-ICR mass spectrometry[BIOTECHNOLOGY AND BIOPROCESS ENGINEERING,2017-09-18] -  Gemcitabine, a broad-spectrum antiviral drug, suppresses enterovirus infections through innate immunity induced by the inhibition of pyrimidine biosynthesis and nucleotide depletion[Oncotarget,2017-12-29] -  Rapid and robust MALDI-TOF MS techniques for microbial identification: a brief overview of their diverse application[JOURNAL OF MICROBIOLOGY,2018-02-28] -  Synthesis and chemical composition analysis of protocatechualdehyde-based novel melanin dye by 15T FT-ICR: High dyeing performance on soft contact lens[DYES AND PIGMENTS,2018-08-29]

특허(최근 5년)

-  Cysteine hydrazide nicotinamide for glycomics and glycoproteomics[2014-03-13] -  Novel N-acetylglucosamine-2-epimerase and method for producing CMP-NeuAc using the same[2014-10-07]

연구과제 수행 실적

말초신경병증 단백체분석 세팔로스포린계 항생제에 대한 다제내성균 내성 고속진단 플랫폼 개발 질량분석기반 천연물 조각이온 검색엔진 범용 시스템 개발 초고분해능 질량분석기를 활용한 기후냉각물질(미세먼지) 화학특성 분석 프로폴리스 지표성분 정밀분석을 통한 원산지 판별 기술 개발 세팔로스포린계 항생제에 대한 다제내성균 내성 고속진단 플랫폼 개발 초고분해능 FT-ICR 질량분석기를 활용한 남.북극 대기 미세입자 분자 특성 연구 고분해능 분석기반 외부유입 미세먼지 유기성분 및 동위원소 지표물질 발굴