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김진수 교수

JIN-SOO KIM

INFO

  • 소속캠퍼스기초과학연구원
  • 전공 기초과학
  • 연락처02-880-9327
  • 출신전공Philosophy in Biochemistry
  • 학위박사
  • 최종출신대학University of Wisconsin, Madison
  • 이메일

연구분야

유전체 교정

Genome Engineering

대표연구실적

-  Genotyping with CRISPR-Cas-derived RNA-guided endonucleases -  Targeted genome engineering in human cells with the Cas9 -  A guide to genome engineering with programmable nucleases

논문(최근 5년)

-  Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration[ GENOME RESEARCH,2017-02-16] -  Generation of a Nrf2 homozygous knockout human embryonic stem cell line using CRISPR/Cas9[Stem Cell Research,2016-12-23] -  A homozygous Keap1-knockout human embryonic stem cell line generated using CRISPR/Cas9 mediates gene targeting[Stem Cell Research,2016-12-23] -  CRISPR/Cpf1-mediated DNA-free plant genome editing[NATURE COMMUNICATIONS,2017-02-16] -  In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni[NATURE COMMUNICATIONS,2017-02-21] -  Generation of cloned adult muscular pigs with myostatin gene mutation by genetic engineering[RSC ADVANCES,2017-02-21] -  Cas-Analyzer: an online tool for assessing genome editing results using NGS data[ BIOINFORMATICS,2016-08-24] -  Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute[ NATURE BIOTECHNOLOGY,2016-11-28] -  DNA-free genetically edited grapevine and apple protoplast using CRISPR/Cas9 ribonucleoproteins[FRONTIERS IN PLANT SCIENCE,2016-12-20] -  Knockout of the ribonuclease inhibitor gene leaves human cells vulnerable to secretory ribonucleases[ BIOCHEMISTRY,2016-11-01] -  Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease[NATURE COMMUNICATIONS,2016-11-02] -  Bypassing GMO regulations with CRISPR gene editing[ NATURE BIOTECHNOLOGY,2016-09-12] -  Genome editing comes of age[NATURE PROTOCOLS,2016-08-04] -  Therapeutic applications of CRISPR RNA-guided genome editing[BRIEFINGS IN FUNCTIONAL GENOMICS,2016-08-25] -  SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells[ONCOTARGET,2016-09-30] -  Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells[ NATURE BIOTECHNOLOGY,2016-07-18] -  A simple, flexible and high-throughput cloning system for plant genome editing via CRISPR-Cas system[JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2016-08-01] -  Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins[ NATURE BIOTECHNOLOGY,2016-06-06] -  Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9[ BIOINFORMATICS,2016-02-24] -  Fine-Tuning Next-Generation Genome Editing Tools[ TRENDS IN BIOTECHNOLOGY,2016-07-01] -  DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins[SCIENTIFIC REPORTS,2016-07-28] -  CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii[SCIENTIFIC REPORTS,2016-06-13] -  Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq[ GENOME RESEARCH,2016-01-19] -  Targeted Genome Editing for Crop Improvement[Plant Breeding and Biotechnology,2015-11-30] -  Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites[ BIOINFORMATICS,2015-09-10] -  Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells[NATURE PROTOCOLS,2015-10-22] -  DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins[ NATURE BIOTECHNOLOGY,2015-10-19] -  Non-GMO genetically edited crop plants[ TRENDS IN BIOTECHNOLOGY,2015-04-01] -  Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9[ CELL STEM CELL,2015-07-23] -  Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells[PRION,2015-07-28] -  Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome[ MOLECULAR CELL,2015-07-02] -  Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9[ MOLECULES AND CELLS,2015-05-19] -  CRISPR germline engineering - The community speaks[ NATURE BIOTECHNOLOGY,2015-06-01] -  Digenome-seq: Genome-wide profiling of CRISPR-Cas9 off-target effects in human cells[ NATURE METHODS,2015-03-10] -  Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus[ DEVELOPMENT GENES AND EVOLUTION,2014-12-30] -  Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles[ PLANTA,2014-10-01] -  Genome engineering in human cells[ METHODS IN ENZYMOLOGY,2014-11-01] -  Targeted gene knockout in chickens mediated by TALENs[ PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2014-09-02] -  Hepatitis C Virus Entry Is Impaired by Claudin-1 Downregulation in Diacylglycerol Acyltransferase-1-Deficient Cells[ JOURNAL OF VIROLOGY,2014-06-04] -  Enrichment of cells with TALEN-induced mutations using surrogate reporters[ METHODS,2014-04-26] -  RNA-Guided Genome Editing in Drosophila with the Purified Cas9 Protein[G3-GENES GENOMES GENETICS,2014-05-19] -  Microhomology-based choice of Cas9 nuclease target sites[ NATURE METHODS,2014-08-06] -  Targeted inversion and reversion of the blood coagulation factor 8 gene in iPS cells using TALENs[ PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2014-06-24] -  Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins[ GENOME RESEARCH,2014-04-02] -  Production of CMAH Knockout Preimplantation Embryos Derived From Immortalized Porcine Cells Via TALE Nucleases[Molecular Therapy - Nucleic Acids,2014-05-27] -  A guide to genome engineering with programmable nucleases[ NATURE REVIEWS GENETICS,2014-04-02]

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