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정창화 교수

Chang Hwa Jung

INFO

  • 소속캠퍼스한국식품연구원
  • 전공 식품생명공학
  • 연락처031-780-9301
  • 출신전공식품생명공학
  • 학위박사
  • 최종출신대학고려대학교
  • 이메일

연구분야

분자영양학, 기능성식품학, 식품생화학

Molecular nutrition

대표연구실적

-  Jung et al., Fisetin regulates obesity by targeting mTORC1 signaling, J Nutr Biochem, 2013 -  ULK1 inhibts the kinase activity of mTORC1 and cell proliferation, Autophagy, 2011 -  ULK1-Atg13-FIP200 complexes mediatemTOR signaling to the autophagy machinery, Mol Biol Cell, 2009

논문(최근 5년)

-  Anthricin Isolated from Anthriscus sylvestris (L.) Hoffm. Inhibits the Growth of Breast Cancer Cells by Inhibiting Akt/mTOR Signaling, and Its Apoptotic Effects Are Enhanced by Autophagy Inhibition.[Evid Based Complement Alternat Med,2013-05-01] -  Limonin enhances osteoblastogenesis and prevents ovariectomy-induced bone loss[JOURNAL OF FUNCTIONAL FOODS,2016-02-05] -  Effects of yuja peel extract and its flavanones on osteopenia in ovariectomized [ MOLECULAR NUTRITION & FOOD RESEARCH,2016-09-20] -  Zingiber mioga reduces weight gain, insulin resistance and hepatic gluconeogenesis in diet-induced obese mice[EXPERIMENTAL AND THERAPEUTIC MEDICINE,2016-05-11] -  Pharmacokinetics of tyrosol metabolites in rats[MOLECULES,2016-01-21] -  Pharmacokinetics, tissue distribution, and anti-lipogenic/adipogenic effects of allyl-isothiocyanate metabolites[PLOS ONE,2015-04-08] -  Shikonin protects against obesity through the modulation of adipogenesis, lipogenesis, and beta-oxidation in vivo[JOURNAL OF FUNCTIONAL FOODS,2015-05-25] -  r-oryzanol enhance adipocyte differentiation and glucose uptake[NUTRIENTS,2015-06-15] -  mTORC1 phosphorylates UVRAGs to negatively regulate autophagosome and endosome maturation[ MOLECULAR CELL,2015-01-22] -  The ULK1 complex mediates mTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14[AUTOPHAGY,2016-01-04] -  Shikonin inhibits adipogenic diiferentiation via regulation of mir-34a-FKBP1B[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-10-22] -  Melatonin ameliorates ER stress-mediated hepatic steatosis through miR-23a in the liver[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-02-07] -  Eleutheroside E, an active compound from Eleutherococcus senticosus, regulates adipogenesis in 3T3-L1 cells[FOOD SCIENCE AND BIOTECHNOLOGY,2014-06-30] -  Cooked rice inhibits hepatic fat accumulation by regulating lipid metabolism-related gene expression in mice fed a high-fat diet[ JOURNAL OF MEDICINAL FOOD,2013-12-04] -  Agaricus bisporus attenuates dextran sulfate sodium-induced colitis[ JOURNAL OF MEDICINAL FOOD,2014-09-05] -  Allyl isothiocyanate ameliorates insulin resistance through the regulation of mitochondria function[ JOURNAL OF NUTRITIONAL BIOCHEMISTRY,2014-05-07] -  Ethanol extract of taheebo attenuates increase in body weight and fatty liver in mice fed a high-fat diet[MOLECULES,2014-10-08] -  curcumin attenuates adhesion molecules and matrix metalloproteinase expression in hyperchloesterolemic rabbits[ NUTRITION RESEARCH,2014-09-04] -  Gingerol sensitizes TRAIL-induced apoptotic cell death of glioblastoma cells[ TOXICOLOGY AND APPLIED PHARMACOLOGY,2014-07-14] -  Distinct functions of ulk1 and ulk2 in the regulation of lipid metabolism in adipocytes[AUTOPHAGY,2013-09-20] -  Quercetin reduces high-fat diet-induced fat accumulation in the liver by regulating lipid metabolism genes[ PHYTOTHERAPY RESEARCH,2013-01-27] -  fisetin regulates obesity by targeting mTORC1 signaling[ JOURNAL OF NUTRITIONAL BIOCHEMISTRY,2013-08-24] -  beta-lapachone prevents diet-induced obesity by incresing energy expenditure and stimulating the browning of white adipose tissue via downregulation of miR-382 expression[ DIABETES,2016-09-02]