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김애영 교수

Aeyung Kim

INFO

  • 소속캠퍼스한국한의학연구원
  • 전공 한의융합의학
  • 연락처053-940-3878
  • 출신전공생명과학
  • 학위박사
  • 최종출신대학한국과학기술원
  • 이메일

연구분야

세포생물학/종양생물학

Cell Biology/Cancer Biology

대표연구실적

-  김애영, 임민주, 구민정, 마진열/Citrus unshiu peel extract alleviates cancer-induced weight loss in mice bearing CT-26 adenocarcinoma/Scientific Reports/2016.04.11 -  김애영, 임민주, 마진열/Ethanol extract of Remotiflori radix induces endoplasmic reticulum stress-mediated cell death through AMPK/mTOR signaling in human prostate cancer cells/Scientific Reports/2015.02.11 -  김애영, 임민주, 임남희, 마진열/Reduction of metastatic and angiogenic potency of malignant cancer by Eupatorium fortunei via suppression of MMP-9 activity and VEGF production/Scientific Reports/2014.11.11

논문(최근 5년)

-  Ethanol extract of Lophatheri Herba exhibits anti-cancer activity in HT1080 cells by suppression of metastatic and angiogenic potential[SCIENTIFIC REPORTS,2016-11-03] -  Ethanol extract of baked Gardeniae Fructus exhibits in vitro and in vivo anti-metastatic and anti-angiogenic activities in malignant cancer cells: role of suppression of the NF-κB and HIF-1α pathways[ INTERNATIONAL JOURNAL OF ONCOLOGY,2016-10-26] -  Citrus unshiu peel extract alleviates cancer-induced weight loss in mice bearing CT-26 adenocarcinoma[SCIENTIFIC REPORTS,2016-04-11] -  Sosiho-tang ameliorates cachexia-related symptoms in mice bearing colon 26 adenocarcinoma by reducing systemic inflammation and muscle loss[ ONCOLOGY REPORTS,2015-12-28] -  Fermented So-Cheong-Ryong-Tang (FCY) induces apoptosis via the activation of caspases and the regulation of MAPK signaling pathways in cancer cells[BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE,2015-09-24] -  Induction of apoptotic cell death by betulin in multidrug-resistant human renal carcinoma cells[ ONCOLOGY REPORTS,2015-06-09] -  The novel herbal cocktail MA128 suppresses tumor growth and the metastatic potential of hghly malignant tumor cells[ ONCOLOGY REPORTS,2015-05-29] -  Jaeumganghwa-tang induces apoptosis via the mitochondrial pathway and Lactobacillus fermentation enhances its anti-cancer activity in HT1080 human fibrosarcoma cells[PLOS ONE,2015-05-28] -  Ethanol extract of Remotiflori radix induces endoplasmic reticulum stress-mediated cell death through AMPK/mTOR signaling in human prostate cancer cells [SCIENTIFIC REPORTS,2015-02-11] -  Reduction of metastatic and angiogenic potency of malignant cancer by Eupatorium fortunei via suppression of MMP-9 activity and VEGF production [SCIENTIFIC REPORTS,2014-11-11] -  Guibitang, a traditional herbal medicine, induces apoptotic death in A431 cells by regulating the activities of mitogen-activated protein kinases[BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE,2014-09-24] -  Anisi stellati fructus extract attenuates the in vitro and in vivo metastatic and angiogenic potential of malignant cancer cells by downregulating proteolytic activity and pro-angiogenic factors[ INTERNATIONAL JOURNAL OF ONCOLOGY,2014-07-21] -  Anti-melanogenic activity of the novel herbal medicine, MA128, through inhibition of tyrosinase activity mediated by the p38 MAPK and PKA signaling pathway in B16F10 cells[PHARMACOGNOSY MAGAZINE,2014-08-30] -  A novel herbal medicine, KIOM-C, induces autophagic and apoptotic cell death mediated by activation of JNK and reactive oxygen species in HT1080 human fibrosarcoma cells[PLOS ONE,2014-05-30]

특허(최근 5년)

-  천연물 추출물을 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 및 건강기능식품(Pharmaceutical composition and functional food for prevention or treatment of cancer comprising herbal extracts)[2015-08-07] -  신곡 추출물을 포함하는 상처 치료용 조성물(Composition for Wound Healing Comprising Massa Medicata Fermentata Extract)[2015-11-30] -  팔각회향 추출물 또는 이의 분획물을 포함하는 암 전이 억제 또는 암 예방용 조성물(Compositions for inhibiting metastasis or preventing cancer comprising Illicium verum Hook.f. extract or fraction thereof)[2015-10-02] -  죽여 추출물을 포함하는 암전이 억제용 약학 조성물(Pharmaceutical compositions having anti-metastasis activity comprising extract of bambusae caulis in taeniam)[2015-06-23] -  황련해독탕 또는 이의 유산균 발효물을 포함하는 암전이 억제용 조성물(A composition for inhibiting cancer metastasis comprising Hwangryunhaedoktang or its product fermented by lactic acid bacteria)[2014-11-21]

연구과제 수행 실적

생물전환을 이용한 신한약제제 개발 종양에 의한 체중감소를 완화시키는 천연물 기반 악액질 개선 소재 발굴 한약재 유래 안구 건조증 질환에 대한 점안제제 개발