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채성욱 교수

Sungwook Chae

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  • 소속캠퍼스한국한의학연구원
  • 전공 한의융합의학
  • 연락처0428689524
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연구분야

천연물화학

Natural product chemistry

대표연구실적

-  Inhibition of UVB-induced wrinkle formation and MMP-9 expression by mangiferin isolated from Anemarrhena asphodeloides -  3-Deoxysappanchalcone inhibits tumor necrosis factor-α-induced matrix metalloproteinase-9 expression in human keratinocytes through activated protein-1 inhibition and nuclear factor-kappa B DNA binding activity -  Effect of compound K, a metabolite of ginseng saponin, combined with gamma-ray radiation in human lung cancer cells in vitro and in vivo

논문(최근 5년)

-  Neuroprotective effects of Psoralea corylifolia Linn seed extracts on mitochondrial dysfunction induced by 3-nitropropionic acid[BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE,2014-10-03] -  한의학 연구동향에 대한 사회연결망분석†[기술혁신학회지,2014-07-02] -  만성스트레스로 유발된 우울증 동물모델에서 오미자 물 추출물의 항우울 효과[대한본초학회지,2014-06-30] -  만성스트레스 모델에서 하엽추출물의 항우울 효과[대한본초학회지,2014-03-20] -  Anti-wrinkle effects of Sargassum muticum ethyl acetate fraction on ultraviolet B-irradiated hairless mouse skin and mechanistic evaluation in the human HaCaT keratinocyte cell line[MOLECULAR MEDICINE REPORTS,2016-08-19] -  Effect of the semen extract of Cuscuta chinensis on inflammatory responses in LPS-stimulated BV-2 microglia[Chinese Journal of Natural Medicines,2014-08-07] -  Induction of Endoplasmic Reticulum Stress via Reactive Oxygen Species Mediated by Luteolin in Melanoma Cells[ ANTICANCER RESEARCH,2016-05-12] -  Fisetin induces apoptosis and endoplasmic reticulum stress in human non-small cell lung cancer through inhibition of the MAPK signaling pathway[ TUMOR BIOLOGY,2016-07-12] -  Rosmarinic Acid Attenuates Cell Damage against UVB Radiation-Induced Oxidative Stress via Enhancing Antioxidant Effects in Human HaCaT Cells[BIOMOLECULES & THERAPEUTICS,2016-01-01] -  Protective effect of fermented Cyclopia intermedia against UVB-induced damage in HaCaT human keratinocytes[BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE,2016-07-29] -  Dual Protective Effects of Flavonoids from Petasites japonicus against UVB-Induced Apoptosis Mediated via HSF-1 Activated Heat Shock Proteins and Nrf2-Activated Heme Oxygenase-1 Pathways[ BIOLOGICAL & PHARMACEUTICAL BULLETIN,2017-06-01] -  Potential for tyndalized Lactobacillus acidophilus as an effective component in moisturizing skin and anti-wrinkle products[ EXPERIMENTAL AND THERAPEUTIC MEDICINE,2016-05-31] -  Timosaponin AIII inhibits melanoma cell migration by suppressing COX-2 and in vivo tumor metastasis[ CANCER SCIENCE,2016-01-22] -  Phloroglucinol Reduces Photodamage in Hairless Mice via Matrix Metalloproteinase Activity Through MAPK Pathway[ PHOTOCHEMISTRY AND PHOTOBIOLOGY,2016-01-20] -  Analysis of the 6-gingerol Content in Zingiber spp. and their Commercial Foods using HPLC[Journal of Applied Biological Chemistry,2015-12-31] -  Orally administered betaine reduces photodamage caused by UVB irradiation through the regulation of matrix metalloproteinase-9 activity in hairless mice[ MOLECULAR MEDICINE REPORTS,2015-11-24] -  Magnolol reduces UVB-induced photodamage byregulating matrix metalloproteinase activity[ ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2014-12-31] -  Anti-wrinkle effects of fermented and nonfermented Cyclopia intermedia in hairless mice[ BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE,2014-10-29]

특허(최근 5년)

-  허니부쉬 추출물 또는 이의 발효액을 유효성분으로 함유하는 피부주름 개선용 조성물[2016-09-14] -  허니부쉬 추출물 또는 이의 발효액을 유효성분으로 함유하는 피부주름 개선용 조성물[2016-09-14] -  틴달화 유산균 사균체를 유효성분으로 포함하는 피부 보습 또는 주름개선용 조성물[2017-05-26] -  피부암 또는 암전이 억제용 조성물[2016-11-02] -  피부 보습 또는 주름 개선용 외용제 조성물 및 화장료 조성물[2016-10-19] -  피부 보습 또는 주름 개선용 외용제 조성물 및 화장료 조성물[2014-03-13] -  한약재 혼합 추출물을 유효성분으로 함유하는 피부 노화 및 주름 개선용 조성물[2017-05-16] -  황련 및 괄루인 혼합 추출물을 유효성분으로 함유하는 피부 노화 및 주름 개선용 조성물[2017-05-16]

연구과제 수행 실적

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