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고윤영 교수

Yun Young Go

INFO

  • 소속캠퍼스한국화학연구원 스쿨
  • 전공 의약화학 및 약리생물학
    (약리생물학)
  • 연락처042-860-7401
  • 출신전공바이러스학
  • 학위박사
  • 최종출신대학University of Kentucky
  • 이메일

연구분야

바이러스성 질병 진단 및 치료제 개발

Development of antivirals and diagnostic tools for viral diseases

대표연구실적

-  Go YY et al/Zoonotic encephalitides caused by arboviruses: transmission and epidemiology of alphaviruses and flaviviruses/Clin Exp Vaccine Res/2014.01 -  Go YY et al/Evidence that in vitro susceptibility of CD3+ T lymphocytes to EAV infection reflects genetic predisposition of naturally infected stallions to become carriers of the virus/J Virol 2012.11 -  Go YY et al./Genome-wide association study among four horse breeds identifies a common haplotype associated with in vitro CD3 T cells susceptible/resistance to EAV infection/J Virol 2011.12

논문(최근 5년)

-  Equine arteritis virus does not induce interferon porduction in equine endothelial cells: identification of nonstructural protein 1 as a main interferon antagonist[Biomed Res Int,2014-05-24] -  Experiences with infectious cDNA clones of equine arteritis virus: lessons learned and insights gained[Virology,2014-08-01] -  Complete genome sequences of three clinical isolates of dengue virus serotype 1 from South Korean Travelers[Genome Announcements,2015-11-25] -  Complete genome sequences of three laboratory strains of dengue virus available in South Korea[Genome Announcements,2015-11-25] -  Equine arteritis virus uses Equine CXCL16 as an entry receptor[ JOURNAL OF VIROLOGY,2016-01-13] -  A pan-dengue reverse transcription insulated isothermal PCR assay intended for point of need diagnosis of dengue virus infection by use of the POCKIT nucleic acid analyzer[ JOURNAL OF CLINICAL MICROBIOLOGY,2016-06-01] -  Antiviral activity of KR-23502 targeting nuclear export of influenza B virus ribonucleoproteins[ ANTIVIRAL RESEARCH,2016-10-01] -  Equinearteritis virus has specific tropism for stromal cells and CD8 T and CD21 B lymphocytes but not for glandular epithelium at the primary site of persistent infection in the stallion reproductive tract [ JOURNAL OF VIROLOGY,2017-06-09] -  Evaluation and clinical validation of two field-deployable reverse transcription-insulated isothermal PCR assays for the detection of the Middle respiratory syndrome coronavirus[ JOURNAL OF MOLECULAR DIAGNOSTICS,2017-11-01] -  Comparison of anti-influenza virus activity and pharmacokinetics of oseltamivir free base and oseltamivir phosphate[The Journal of Microbiology,2017-12-01] -  Systematic editing of synthetic RIG-I ligands to produce effective antiviral and anti-tumor RNA immunotherapies[ NUCLEIC ACIDS RESEARCH,2018-01-26]

연구과제 수행 실적

플라비바이러스에 대한 화합물 약효검색시험