Field of Research
Medicinal Chemistry, Organic Chemistry, Asymmetric Synthesis
- Se-Mi Son, Hyeon-Kyu Lee,* “Dynamic Kinetic Resolution Based Asymmetric Transfer Hydrogenation of 2-Benzoyl-Morpholinones and Its Use in Concise Stereoselective Synthesis of All Four Stereoisomers of the Anti-depressant Reboxetine”, J. Org. Chem. 2013, 78, 8396.
- Juae Han, Soyeong Kang, Hyeon-Kyu Lee.* “Dynamic Kinetic Resolution in the Stereoselective Synthesis of 4,5-Diaryl Cyclic Sulfamidates by Using Chiral Rhodium-Catalyzed Asymmetric Transfer Hydrogenation”, Chem. Comm., 2011, 47, 4004-4006.
- Hyeon-Kyu Lee*, Eun Bok Choi, and Chwang Siek Pak, “The Current Status and Future Perspectives of Studies of Cannabinoid Receptor 1 Antagonists as Anti-Obesity Agents.” Curr. Top. Med. Chem. 2009, 9, 482-503.
- Stereoselective synthesis of 4-substituted-cyclic sulfamidate-5-carboxylates by asymmetric transfer hydrogenation accompanied by dynamic kinetic resolution and applications[Chemical Communications,2014-09-05]
- Xanthene Derivatives Increase Glucose Utilization through Activation of LKB1-Dependent AMP Activated Protein Kinase[PLoS ONE,2014-09-24]
- Stereoselective Synthesis of 4-Substituted Cyclic Sulfamidate-5-Phosphonates by Using Rh Catalyzed Asymmetric Transfer Hydrogenation with Accompanying Dynamic Kinetic Resolution[J. Organic Chemistry,2015-08-17]
- Stereoselective synthesis of 1,3-disubstituted isoindolines via Rh(III)-catalyzed tandem oxidative olefination-cyclization of 4-aryl cyclic sulfamidates[ CHEMICAL COMMUNICATIONS,2016-01-27]
- Stereoselective synthesis of functionalized 1,3-disubstituted isoindolines via Rh(III)-catalyzed tandem oxidative olefination-cyclization of 4-aryl-cyclic sulfamidate-5-carboxylates[ JOURNAL OF ORGANIC CHEMISTRY,2017-07-03]
- Tandem Rh-catalyzed oxidative C-H olefination and cyclization of enantiomerically enriched benzo-1,3-sulfamidates: Stereoselective synthesis of trans-1,3-disubstituted isoindolines[JOURNAL OF ORGANIC CHEMISTRY,2018-03-15]
- DBU-Promoted Dynamic Kinetic Resolution in Rh-Catalyzed Asymmetric Transfer Hydrogenation of 5-Alkyl Cyclic Sulfamidate Imines: Stereoselective Synthesis of Functionalized 1,2-Amino Alcohols[JOURNAL OF ORGANIC CHEMISTRY,2018-09-10]
- 고 입체순도를 갖는 4-알킬-5-아릴 5-원고리 설파미데이트의 제조방법[2014-09-24]
- 카나비노이드 수용체（ＣＢ１） 길항제로서의 헤테로고리 벤즈아미드 유도체[2014-09-29]
- 2-치환된 몰포린 입체 이성질체의 선택적 제조방법[2015-03-20]
- 당뇨병 치료용 약학적 조성물[2017-05-11]
- 신규한 벤조옥사졸 유도체, 이의 제조방법 및 이를 함유하는 약학 조성물[2015-05-22]
- 1.3-치환된 이소인돌린 유도체 및 이의 입체선택적 제조방법[2017-12-06]
- 고 입체순도를 갖는 4-치환된-5-원고리-설파미데이트-5-포스포네이트 화합물 및 이의 제조방법[2017-12-28]