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김한우 교수

KIM, Han-Woo

INFO

  • 소속캠퍼스극지연구소
  • 전공 극지과학
  • 연락처032-760-5526
  • 출신전공분자생물학
  • 학위박사
  • 최종출신대학부산대학교
  • 이메일

연구분야

단백질 공학

Protein Engineering

대표연구실적

-  Crystal structure of cis-dihydrodiol naphthalene dehydrogenase (NahB) from Pseudomonas sp. MC1: Insights into the early binding process of the substrate.Biochem Biophys Res Commun. 2017 -  Structure and catalytic mechanism of monodehydroascorbate reductase, MDHAR, from Oryza sativa L. japonica. Sci Rep. 2016 -  Atomic resolution of the crystal structure of the hyperthermophilic family 12 endocellulase and stabilizing role of the DxDxDG calcium-binding motif in Pyrococcus furiosus. FEBS Lett. 2012

논문(최근 5년)

-  Identification of Proteolytic Bacteria from the Arctic Chukchi Sea Expedition Cruise and Characterization of Cold-active Proteases[J. Microbiology,2014-07-21] -  Enhancing Extracellular Lipolytic Enzyme Production In An Arctic Bacterium, Psychrobacter sp. ArcL13, By Using Statistical Optimization And Fed-Batch Fermentation[ PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY,2015-02-01] -  Crystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes.[ SCIENTIFIC REPORTS,2015-02-03] -  Cold adaptation of a psychrophilic chaperonin from Psychrobacter sp. and its application for heterologous protein expression.[ BIOTECHNOLOGY LETTERS,2015-05-24] -  Combining biomass wet disk milling and endoglucanase/β-glucosidase hydrolysis for the production of cellulose nanocrystals.[ CARBOHYDRATE POLYMERS,2015-09-05] -  Expression, refolding, and characterization of a small laccase from Thermus thermophilus HJ6.[ PROTEIN EXPRESSION AND PURIFICATION,2015-06-11] -  Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica.[ SCIENTIFIC REPORTS,2016-01-18] -  Comparative Analysis of Lacinutrix Genomes and Their Association with Bacterial Habitat.[ PLOS ONE,2016-02-16] -  Complete genome sequence of the crude oil-degrading thermophilic bacterium Geobacillus sp. JS12.[ JOURNAL OF BIOTECHNOLOGY,2016-05-13] -  Crystal structures of aldehyde deformylating oxygenase from Limnothrix sp. KNUA012 and Oscillatoria sp. KNUA011.[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-06-18] -  Potential Application of the Oryza sativa Monodehydroascorbate Reductase Gene (OsMDHAR) to Improve the Stress Tolerance and Fermentative Capacity of Saccharomyces cerevisiae.[ PLOS ONE,2016-07-08] -  Biochemical and structural characterization of quinoprotein aldose sugar dehydrogenase from Thermus thermophilus HJ6: Mutational analysis of Tyr156 in the substrate-binding site.[ ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS,2016-08-31] -  Structure and catalytic mechanism of monodehydroascorbate reductase, MDHAR, from Oryza sativa L. japonica.[ SCIENTIFIC REPORTS,2016-09-22] -  Characterization of Two Antimicrobial Peptides from Antarctic Fishes (Notothenia coriiceps and Parachaenichthys charcoti)[ PLOS ONE,2017-01-25] -  Crystal Structure and Functional Characterization of an Esterase (EaEST) from Exiguobacterium antarcticum.[ PLOS ONE,2017-01-26] -  Crystal structure of the inactive state of the receiver domain of Spo0A from Paenisporosarcina sp. TG-14, a psychrophilic bacterium isolated from an Antarctic glacier.[ JOURNAL OF MICROBIOLOGY,2017-01-25] -  Crystal structure of cis-dihydrodiol naphthalene dehydrogenase (NahB) from Pseudomonas sp. MC1: Insights into the early binding process of the substrate.[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2017-07-17] -  Crystallization and preliminary X-ray crystallographic studies of dehydroascorbate reductase (DHAR) from Oryza sativa L. japonica.[ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS,2014-05-24] -  Purification, characterization and preliminary X-ray crystallographic studies of monodehydroascorbate reductase from Oryza sativa L. japonica.[ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS,2014-07-08] -  PsEst3, a new psychrophilic esterase from the Arctic bacterium Paenibacillus sp. R4: crystallization and X-ray crystallographic analysis.[ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS,2018-05-31] -  Biochemical characterization of a thermostable cobalt- or copper-dependent polyphenol oxidase with dye decolorizing ability from Geobacillus sp. JS12[ENZYME AND MICROBIAL TECHNOLOGY,2018-06-28] -  Properties of phase transition of ice binding protein from Arctic yeast (LeIBP) utilizing differential scanning calorimetry (DSC) and Raman spectroscopy[CRYOBIOLOGY,2018-10-05]

연구과제 수행 실적

극지유전체 101 프로젝트: 극지생물 유전체 정보 분석 및 활용기반 구축 북극권 동토 관측 거점유래 고분자 유기 탄소 화합물 분해관련 유용 저온효소 활용연구