본문 바로가기 대메뉴 바로가기
Jun Hyuck Lee(Professor)

INFO

  • AffiliationKorea Polar Research Institute
  • Majors Polar Science
  • Contact Information032-760-5555
  • Major생명과학과
  • DegreePh.D.
  • Highest Level of Education광주과학기술원
  • E-Mail

Field of Research

Structural and functional studies on cold-active proteins

Research Results

-  Do H, Kim S-J, Kim HJ, Lee JH*. Structure-based characterization and antifreeze properties of a hyperactive ice-binding protein fromthe Antarctic bacterium Flavobacterium frigoris PS1. Acta Crystallogr D Biol Crystallogr. 2014, D70, 1061-1073 -  Lee JH*, Park AK*, Do H, Park KS, Moh SH, Chi YM, Kim HJ. Structural basis for the antifreeze activity of an ice-binding protein from an Arctic yeast. J Biol Chem. 2012;287;11460-11468 -  Lee JH, Rangarajan ES, Yogesha SD, Izard T. Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure. 2009;17:833-842.

Treatise

-  Structure-based characterization and antifreeze properties of a hyperactive ice-binding protein fromthe Antarctic bacterium Flavobacterium frigoris PS1.[Acta Crystallogr D Biol Crystallogr.,2014-04-01] -  Crystallization and preliminary X-ray crystallographic studies of dehydroascorbate reductase (DHAR) from Oryza sativa L. japonica.[Acta Crystallogr F Struct Biol Commun.,2014-06-01] -  Purification characterization and preliminary X-ray crystallographic studies of monodehydroascorbate reductase from Oryza sativa L. japonica.[Acta Crystallogr Sect F Struct Biol Cryst Commun,2014-09-01] -  The protective role of antifreeze protein 3 on the structure and function of mature mouse oocytes in vitrification.[Genome Biology,2014-09-25] -  Molecular Mechanisms of Host Cytoskeletal Rearrangements by Shigella Invasins[International Journal of Molecular Sciences,2014-10-10] -  Production of Antifreeze Protein from Antarctic Bacterium Flavobacterium frigoris PS1 by using Fed-batch Culture of Recombinant Pichia pastoris[Korean Society for Biotechnology and Bioengineering Journal,2014-07-31] -  Effect of the antifreeze protein from the arctic yeast Leucosporidium sp. AY30 on cryopreservation of the marine diatom Phaeodactylum tricornutum.[ APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY,2015-01-01] -  Crystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes[ SCIENTIFIC REPORTS,2015-02-03] -  Crystal structure of human POP1 and its distinct structural feature for PYD domain[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-05-15] -  Cold adaptation of a psychrophilic chaperonin from Psychrobacter sp. and its application for heterologous protein expression[ BIOTECHNOLOGY LETTERS,2015-09-01] -  Effects of antifreeze proteins on the vitrification of mouse oocytes: comparison of three different antifreeze proteins[ HUMAN REPRODUCTION,2015-09-01] -  Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-09-11] -  Ice-Binding Protein Derived from Glaciozyma Can Improve the Viability of Cryopreserved Mammalian Cells[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2015-12-28] -  Crystal Structure and Comparative Sequence Analysis of GmhA from Colwellia psychrerythraea Strain 34H Provides Insight into Functional Similarity with DiaA[ MOLECULES AND CELLS,2015-12-01] -  A transcriptomic analysis of the response of the arctic pteropod Limacina helicina to carbon dioxide-driven seawater acidification[ POLAR BIOLOGY,2015-06-17] -  Pilot-scale Production of the Antifreeze Protein from Antarctic Bacte?rium Flavobacterium frigoris PS1 by Recombinant Escherichia coli with a Cold Shock Induction System[KSBB Journal,2015-11-26] -  Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica[SCIENTIFIC REPORTS,2016-01-18] -  Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis[SCIENTIFIC REPORTS,2016-01-25] -  Crystal structure and modeling of the tetrahedral intermediate state of methylmalonate-semialdehyde dehydrogenase (MMSDH) from Oceanimonas doudoroffii[JOURNAL OF MICROBIOLOGY,2016-02-01] -  Molecular mechanism of constitutively active Rab11A was revealed by crystal structure of Rab11A S20V[FEBS LETTERS,2016-03-01] -  Complete genome sequence of the crude oil-degrading thermophilic bacterium Geobacillus sp. JS12[ JOURNAL OF BIOTECHNOLOGY,2016-07-20] -  Crystal Structure of Cytochrome P450 (CYP105P2) from Streptomyces peucetius and Its Conformational Changes in Response to Substrate Binding[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2016-05-25] -  Crystal structures of aldehyde deformylating oxygenase from Limnothrix sp. KNUA012 and Oscillatoria sp. KNUA011[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-08-26] -  Structure and catalytic mechanism of monodehydroascorbate reductase, MDHAR, from Oryza sativa L. japonica[SCIENTIFIC REPORTS,2016-09-22] -  Proteomic and transcriptomic investigations on cold-responsive properties of the psychrophilic Antarctic bacterium Psychrobacter sp. PAMC 21119 at subzero temperatures[ENVIRONMENTAL MICROBIOLOGY,2017-02-01] -  Biophysical characterization of soluble Pseudomonas syringae ice nucleation protein InaZ fragments[ INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2017-01-01] -  Controlled dehydration improves the diffraction quality of two RNA crystals[ BMC STRUCTURAL BIOLOGY,2016-11-03] -  Crystal Structure of a Putative Cytochrome P450 Alkane Hydroxylase (CYP153D17) from Sphingomonas sp. PAMC 26605 and Its Conformational Substrate Binding[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2016-12-09] -  Characterization of Two Antimicrobial Peptides from Antarctic Fishes (Notothenia coriiceps and Parachaenichthys charcoti)[PLOS ONE,2017-01-25] -  Crystal Structure and Functional Characterization of an Esterase (EaEST) from Exiguobacterium antarcticum[PLOS ONE,2017-01-26] -  Marine Antifreeze Proteins: Structure, Function, and Application to Cryopreservation as a Potential Cryoprotectant[MARINE DRUGS,2017-01-27] -  Crystal structure of the inactive state of the receiver domain of Spo0A from Paenisporosarcina sp. TG-14, a psychrophilic bacterium isolated from an Antarctic glacier[JOURNAL OF MICROBIOLOGY,2017-06-01] -  The genome of the Antarctic-endemic copepod, Tigriopus kingsejongensis[GIGASCIENCE,2017-01-01] -  Crystal Structure and Functional Characterization of a Cytochrome P450 (BaCYP106A2) from Bacillus sp. PAMC 23377[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2017-08-28] -  Crystal structure and functional characterization of an isoaspartyl dipeptidase (CpsIadA) from Colwellia psychrerythraea strain 34H[PLOS ONE,2017-07-19] -  Crystal structure of cis-dihydrodiol naphthalene dehydrogenase (NahB) from Pseudomonas sp. MC1: Insights into the early binding process of the substrate[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2017-09-16] -  Crystal structure of 5-enolpyruvylshikimate-3-phosphate synthase from a psychrophilic bacterium, Colwellia psychrerythraea 34H[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2017-10-21] -  Improving thermal hysteresis activity of antifreeze protein from recombinant Pichia pastoris by removal of N-glycosylation[ PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY,2017-03-16]

Patent

-  루코스포리디움 속 미생물 유래 단백질을 포함하는 동결 보존용 조성물 및 이를 이용한 동결 손상 방지 방법 [2017-08-02] -  플라보박테리움 프리고리스 유래 결빙방지 단백질[2015-02-02]