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박상현 교수

Park Sang Hyun

INFO

  • 소속캠퍼스한국원자력연구원
  • 연락처063-570-3370
  • 출신전공화학
  • 학위박사
  • 최종출신대학Stevens Institute of Technology
  • 이메일

연구분야

신약 개발

Drug discovery and development

대표연구실적

-  K. C. Ko, M. H. Choi, J. K. Rho and S. H. Park, "A facile method for detecting calcium/calmodulin-dependent protein kinase using radio phosphorylation of a GBP-fused enzyme substrate in a lab-on-a-chip", Sensor. Actuat. B-Chem., Vol. 178, pp. 432-442, Mar., 2013. -  K. Pradeep, K. C. Ko, M. H. Choi, J. A. Kang, Y. J. Chung and S. H. Park, "Protective effect of hesperidin, a flavanoglycone, against γ-radiation-induced tissue damage in Sprague-Dawley rats", J. Med. Food, Vol. 15, No. 5, pp. 419-427, May, 2012. -  J. K. Rho, J. A. Kang, M. H. Choi, K. C. Ko and S. H. Park, "Enhanced kinase sensing by radio-phosphorylation and oriented immobilization of a GBP-linked kinase substrate on a gold surface", Sensor. Actuat. B-Chem., Vol. 160, pp. 632-636, Aug., 2011.

논문(최근 5년)

-  A facile method for detecting calcium/calmodulin-dependent protein kinase using radio phosphorylation of a GBP-fused enzyme substrate in a lab-on-a-chip[Sensors and actuators. B, Chemical,2013-03-01] -  In Vivo Molecular Imaging of [125I]-Labeled 3-Iodothyronamine: A Hibernation-Inducing Agent[Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry, and medicine,2013-01-31] -  Anti-inflammatory action of γ-irradiated genistein in murine peritoneal macrophage[Radiation Physics and Chemistry,2014-06-12] -  Antioxidative activities of Ginkgo biloba extract in oil/water emulsion system prepared from an enzymatically modified lipid containing[Journal of Food Science,2013-01-15] -  Biodistribution of 99mTc tricarbonyl glycine oligomers[Toxicology Research,2012-12-03] -  Effect of ionizing irradiation on in vitro cytotoxic and nitric oxide producing abilities of mistletoe (Viscum Album) extract[Italian Journal of Food Science,2012-12-03] -  Emulsifying properties of lecithin containing different fatty acids obtained by immobilized lecitase ultra-catalyzed reaction[Journal of the American Oil Chemistry Society,2013-12-17] -  Hesperidin and Curdlan treatment ameliorates γ-radiation induced cellular damage and oxidative stress in the liver of Sprague-Dawley rats[Research Journal of Pharmaceutical, Biological and chemical Sciences,2014-07-01] -  Immune-enhancing activity of silk peptide in a gamma ?irradiated mouse model[Italian Journal of Food Science,2012-12-03] -  In Vivo molecular imaging of [125I]-labeled 3-iodothyronamine: A Hibernation-inducing agent[Applied Radiation and Isotopes,2012-12-13] -  Preparation of recombined milk using modified butterfats containing α-linolenic acid[Journal of Food Science,2013-01-15] -  Procyanidin C1 causes vasorelaxation through activation of the endothelial NO/cGMP pathway in thoracic aortic rings[Journal of Medicinal Food,2014-03-23] -  Procyanidin dimer B2-mediated IRAK-M induction negatively regulates TLR4 signaling in macrophages[Biochemical and Biophysical Rsearch Communications,2013-07-16] -  Radoprotective effects of silk peptide on Raw264.7 macrophage cells[Italian Journal of Food Science,2012-12-03] -  The procyanidin trimer C1 induces macrophage activation via NF-kB and MAPK pathways, leading to Th1 polarization in murine splenocytes[European Journal of Pharmacology,2013-06-13] -  The procyanidin trimer C1 inhibits LPS-induced MAPK and NF-kB signaling through TLR4 in macrophages[International Immunopharmacology,2012-12-20]

특허(최근 5년)

-  방사선 조사를 이용하여 저장 안정성이 개선된 알로에 추출물을유효성분으로 함유하는 조성물 및 이의제조방법[2014-08-19] -  전도성 나노복합체 및 이의 제조방법[2013-12-24] -  전도성 나노복합체 및 이의 제조방법[2014-07-18] -  테크네튬-99m 트리카보닐 표지 글리신 단량체 또는 올리고머를 활용 생리활성분자를 이용한 프로브의 제조방법 및 이를 포함하는 영상제 조성물[2012-11-05] -  테크네튬-99엠이 표지된 금 나노입자-금결합 펩타이드 복합체 제조 방법, 그 방법에 의해 제조된 복합체 및 이의 용도[2014-04-16] -  티올기 검출을 위한 바이오 센서 및 이의제조방법[2012-09-26] -  헤스페리딘을 유효성분으로 함유하는 세포보호용 조성물[2013-08-27]