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김민규 교수

Min-Kyu Kim

INFO

  • 소속캠퍼스한국원자력연구원
  • 전공 방사선동위원소 응용 및 생명공학
  • 연락처063-570-3212
  • 출신전공생명과학부
  • 학위박사
  • 최종출신대학서울대학교
  • 이메일

연구분야

미생물학, 생화학, 구조생물학

Microbiology, Biochemistry, Structural Biology

대표연구실적

-  Kim, M.-K.*, An, Y.J.*, Na, J.-H.*, Seol, J.-H., Ryu, J.Y., Lee, J.-W., Kang, L.-W., Chung, K.M., Lee, J.-H., Moon, J.H., Lee, J.S. and Cha, S.-S.* (2017) Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine. J Antimicrob Chemother. 72(3):735-743 -  Kim, M.-K.*, Kim, J.-H.*, Kim, J.-S.* and Kang, S.-O. (2015) Structure of the 34 kDa F-actin-bundling protein ABP34 from Dictyostelium discoideum. Acta Crystallogr D Biol Crystallogr. 71(Pt 9):1835-1849. -  Kim, M.-K., An, Y.J., Song, J.M., Jeong, C.-S., Kang, M.H., Kwon, K.K., Lee, Y.-H. and Cha, S.-S. (2014). Structure-based investigation into the functional roles of the extended loop and substrate-recognition sites in an endo-β-1,4-D-mannanase from the Antarctic springtail, Cryptopygus antarcticus. Proteins. 82(11):3217-3223.

논문(최근 5년)

-  PprM is necessary for up-regulation of katE1, encoding the major catalase of Deinococcus radiodurans, under unstressed culture conditions[JOURNAL OF MICROBIOLOGY,2016-06-01] -  The three catalases in Deinococcus radiodurans: Only two show catalase activity [ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-12-01] -  Structure of the 34 kDa F-actin-bundling protein ABP34 from Dictyostelium discoideum[ ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY,2015-09-01] -  Structure-based investigation into the functional roles of the extended loop and substrate-recognition sites in an endo-β-1,4-D-mannanase from the Antarctic springtail, Cryptopygus antarcticus [ PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS,2014-11-01] -  Cyclic dipeptides from lactic acid bacteria inhibit the proliferation of pathogenic fungi [JOURNAL OF MICROBIOLOGY,2014-01-01] -  Cyclic dipeptides from lactic acid bacteria inhibit proliferation of the influenza A virus [JOURNAL OF MICROBIOLOGY,2013-12-01] -  Structural basis for the β-lactamase activity of EstU1, a family VIII carboxylesterase [ PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS,2013-11-01] -  Experimental phasing using zinc and sulfur anomalous signals measured at the zinc absorption peak [JOURNAL OF MICROBIOLOGY,2013-10-01] -   The crystal structure of a novel phosphopantothenate synthetase from the hyperthermophilic archaea, Thermococcus onnurineus NA1 [ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2013-09-01] -  Expression at 279 K, purification, crystallization and preliminary X-ray crystallographic analysis of a novel cold-active β-1,4-D-mannanase from the Antarctic springtail Cryptopygus antarcticus [ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS,2013-09-01] -  In-house zinc SAD phasing at Cu K alpha edge [ MOLECULES AND CELLS,2013-05-01] -  Unraveling fungal radiation-resistance regulatory networks through the genome-wide transcriptome and genetic analyses of Cryptococcus neoformans[MBIO,2016-11-29] -  Structural and mechanistic insights into the inhibition of class C β-lactamases through the adenylylation of the nucleophilic serine[JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY,2017-03-01]

특허(최근 5년)

-  아연을 이용한 단백질 구조 결정 방법[2014-07-30]