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정재훈 교수

JEONG, Jae-Hoon

INFO

  • 소속캠퍼스한국원자력의학원
  • 전공 방사선종양의과학
  • 직급전공책임교수
  • 연락처02-970-1386
  • 출신전공미생물학
  • 학위박사
  • 최종출신대학서울대학교
  • 이메일

연구분야

방사선생물학, 종양생물학, 세포분자생물학, 신호전달

Radiobiology, Cancer biology, Cellualr molecular biology, Signal transduction

대표연구실적

-  Young-Joo Shin, Mi-Sook Kim, Moon Sun Kim, Joonseok Lee, Mi Ae Kang, and Jae-Hoon Jeong/High-mobility group box 2 (HMGB2) protein modulates radioresponse and is downregulated by p53 in colorectal cancer cells./Cancer Biol Ther. 14(3): 213-221 (2013 Mar) -  Hye Kyung Shin, Mi-Sook Kim, Jin Kyung Lee, Seung-Sook Lee, Young Hoon Ji, Jong-Il Kim, and Jae-Hoon Jeong/Combination effect of cetuximab with radiation in colorectal cancer cells./Tumori 96(5):713-720 (2010 Sep-Oct) -  Tae-Joon Hong, Sangkyu Kim, Ah Ram Wi, Peter Lee, Miae Kang, Jae-Hoon Jeong, and Ji-Sook Hahn/Dynamic Nucleotide-dependent Interactions of Cysteine and Histidine Rich Domain (CHORD)-containing Hsp90 Cochaperones Chp-1 and Melusin with Cochaperones PP5 and Sgt1./J. Biol. Chem. 288(1):215-222 (2013 Jan)

논문(최근 5년)

-  Low and high linear energy transfer radiation sensitization of HCC cells by metformin[JOURNAL OF RADIATION RESEARCH,2014-05-01] -  β,β-Dimethylacrylshikonin sensitizes human colon cancer cells to ionizing radiation through the upregulation of reactive oxygen species[ONCOLOGY LETTERS,2014-06-02] -  Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2014-07-25] -  A novel pyrido-thieno-pyrimidine derivative activates p53 through induction of phosphorylation and acetylation in colorectal cancer cells[ INTERNATIONAL JOURNAL OF ONCOLOGY,2015-01-01] -  Suppressor of Cytokine Signaling (SOCS) Genes Are Silenced by DNA Hypermethylation and Histone Deacetylation and Regulate Response to Radiotherapy in Cervical Cancer Cells.[PLOS ONE,2015-04-07] -  Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells.[Clinical and molecular hepatology,2015-03-02] -  Radiobiological mechanisms of stereotactic body radiation therapy and stereotactic radiation surgery[Radiation Oncology Journal,2015-12-30] -  Lanatoside C suppressed colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair.[ONCOTARGET,2016-02-02] -  XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence.[ONCOTARGET,2016-02-02] -  GDF15 contributes toradiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells[ONCOTARGET,2016-03-01] -  In vivo monitoring of CD44+ cancer stem-like cells by γ-irradiation in breast cancer[ INTERNATIONAL JOURNAL OF ONCOLOGY,2016-06-01]

특허(최근 5년)

-  유전자의 발현을 활성화하는 피리도싸이에노피리미딘 유도체 및 그를 함유하는 암 예방 및 치료용 약학 조성물[2016-09-01]