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Kim Kwang Seok(Professor)

INFO

  • AffiliationKorea Institute of Radiological & Medical Sciences
  • Majors Radiological & Medico-Oncological Sciences
  • Contact Information02-970-1393
  • Major분자세포생물학전공
  • DegreePh.D.
  • Highest Level of Education경북대학교
  • E-Mail

Field of Research

radiation-induced endothelial senescence and aging-associated vascular disease

Research Results

-  Kwang Seok Kim, Jung Eun Kim, Kyu Jin Choi, Sangwoo Bae, Dong Ho Kim. Characterization of DNA Damage-Induced Cellular Senescence by Ionizing Radiation in endothelial cells. Int J Radiat Biol 90(1): 71?80, 2014.1 -  Kwang Seok Kim, Young Bae Seu, Suk-Hwan Baek, Mi Jin Kim, Keuk Jun Kim, Jung Hye Kim, and Jae-Ryong Kim. Induction of Cellular Senescence by Insulin-like Growth Factor Binding Protein-5 through a p53-dependent Mechanism. Mol. Biol. Cell 18(11) 4543-4552. 2007.11 -  Kwang Seok Kim, Min-Sun Kim, Young-Bae Seu, Suk-Hwan Baek, Jung Hye Kim, and Jae-Ryong Kim. The role of Insulin-like growth factor binding protein-3 in cellular senescence of human umbilical vein endothelial cell. Aging Cell 6(4) 537 ? 547. 2007.2

Treatise

-  Enhancement of cellular radiation sensitivity through degradation of Chk1 by the XIAP-XAF1 complex[Cancer Biology and Therapy,2014-12-23] -  Induction of interleukin-1 beta (IL-1β) is a critical component of lung inflammation during influenza A (H1N1) virus infection[Journal of Medical Virology,2015-03-19] -  XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence[Oncotarget,2016-01-21] -  GDF15 contributes to radiation-induced senescence through the ros-mediated p16 pathway in human endothelial cells[Oncotarget,2016-02-23] -  In vivo monitoring of CD44+ cancer stem-like cells by γ-irradiation in breast cancer[ INTERNATIONAL JOURNAL OF ONCOLOGY,2016-03-03] -  A novel Chk1-binding peptide that can enhance genotoxic sensitivity through cellular redistribution of nuclear Chk1[ INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,2016-09-21]

Patent

-  IGFBP-5 a marker for diagnosing radiation exposure a composition for diagnosing radiation exposure to measure the level of expression of the marker a kit for diagnosing radiation exposure[2014-06-27]