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이승식 교수

Seung Sik Lee

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  • 소속캠퍼스한국원자력연구원
  • 전공 방사선 과학기술
  • 연락처063-570-3332
  • 출신전공응용생명과학(생화학)
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연구분야

방사선생물학

Radiation Biology

대표연구실적

-  이승식 외/Effects of irradiation on decolourisation and biological activity in Schizandra chinensis extracts/Food Chem/2011.03.01 -  이승식 외/Degradation of cyanidin-3-rutinoside and formation of protocatechuic acid methyl ester in methanol solution by gamma irradiation/Food Chem/2014.08.01 -  이승식 외/Site-directed mutagenesis substituting cysteine for serine in 2-Cys peroxiredoxin (2-Cys Prx A) of Arabidopsis thaliana effectively improves its peroxidase and chaperone functions/Annals of Botany/2015.09.30

논문(최근 5년)

-  Degradation of cyanidin-3-rutinoside and formation of protocatechuic acid methyl ester in methanol solution by gamma irradiation[Food Chem.,2014-08-01] -  Developmental inhibition of gamma irradiation on the peach fruit moth Carposina sasakii (Lepidoptera: Carposinidae)[Radiat. Phys. Chem.,2015-01-01] -  Liquid chromatography-tandem mass spectrometry-assisted identification of two salinity-inducible ascorbate peroxidases in a salt-sensitive rice cultivar (Oryza sativa L. cv. ‘IR-29’)[Plant Growth Regul.,2015-01-06] -  An additional cysteine in a typical 2-Cys peroxiredoxin of Pseudomonas promotes functional switching between peroxidase and molecular chaperone[FEBS Letters,2015-09-11] -  Site-directed mutagenesis substituting cysteine for serine in 2-Cys peroxiredoxin (2-Cys Prx A) of Arabidopsis thaliana effectively improves its peroxidase and chaperone functions[Annals of Botany,2015-09-30] -  Protective effect of centipedegrass against Aβ oligomerization and Aβ-mediated cell death in PC12 cells[PHARMACEUTICAL BIOLOGY,2015-04-08] -  Enhancement of chaperone activity of plant-specific thioredoxin through γ-ray mediated conformational change[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2015-11-12] -  Characterization of histone modifications associated with DNA damage repair genes upon exposure to gamma rays in Arabidopsis seedlings[JOURNAL OF RADIATION RESEARCH,2016-08-16] -  Enhancement of the chaperone activity of alkyl hydroperoxide reductase C from Pseudomonas aeruginosa PAO1 resulting from a point-specific mutation confers heat tolerance in Escherichia coli[MOLECULES AND CELLS,2016-08-31] -  Site-specific mutagenesis of yeast 2-Cys peroxiredoxin improves heat or oxidative stress tolerance by enhancing its chaperone or peroxidase function[PROTOPLASMA,2017-01-01] -  Maysin and its flavonoid derivative from Centipedegrass attenuates amyloid plaques by inducting humoral immune response with a Th2-skewed cytokine response in the Tg (APPswe, PS1dE9) Alzheimer's mouse model[PLOS ONE,2017-01-10] -  Gamma irradiation-assisted degradation of rosmarinic acid and evaluation of structures and anti-adipogenic properties[FOOD CHEMISTRY,2018-08-30] -  A Pyridazine-based fluorescent probe targeting Aβ plaques in Alzheimer’s disease[JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY,2018-02-27] -  Gamma irradiation of aloe-emodin induced structural modification and apoptosis through a ROS- and caspase-dependent mitochondrial pathway in stomach tumor cells[INTERNATIONAL JOURNAL OF RADIATION BIOLOGY,2018-03-06] -  Improvement of physiological activity and processing quality through structural transformation of natural biomaterials based on radiation technology [Korean Journal of Food Science and Technology,2018-05-31] -  Functional switching of ascorbate peroxidase 2 of rice (OsAPX2) between peroxidase and molecular chaperone[SCIENTIFIC REPORTS,2018-06-15] -  Confirmation of no causal relationship between genome-wide DNA methylation and transcriptome changes after gamma irradiation [방사선산업학회지,2017-12-30]

특허(최근 5년)

-  바이오매스의 당화효율을 증진하기 위한 전처리 방법 및 이를 이용한 바이오에탄올의 제조방법[2014-04-25] -  양성자 조사를 이용한 퍼옥시레독신의 퍼옥시다제 및 샤페론 활성 동시 증가 방법[2014-05-12] -  방사선 조사를 이용한 퍼옥시레독신의 샤페론 활성 생성 방법[2014-05-12] -  센티페드그라스 추출물 또는 이의 분획물을 유효성분으로 함유하는 피부 질환 개선용 조성물[2014-05-16] -  센티페드그라스 추출물 또는 이의 분획물을 유효성분으로 함유하는 면역 증강용 조성물[2014-05-22] -  신규한 로테논 유도체 및 이를 유효성분으로 함유하는 비만 예방 및 치료용 약학적 조성물[2014-07-06] -  방사선을 이용한 리모넨의 제거 방법[2014-11-19] -  방사선 조사를 이용한 퍼옥시레독신의 샤페론 활성 조절방법[2015-01-23] -  Method for controlling the chaperone activity of peroxiredoxins using irradiation[2015-11-10] -  슈도모나스 애루지노사의 AhpF 단백질의 신규 활성 및 이의 용도[2015-12-07] -  Rotenone derivatives and a use thereof[2016-05-03] -  센티페드그라스 추출물을 유효성분으로 함유하는 골 질환 예방 및 치료용 약학적 조성물[2016-06-29] -  Composition comprising centipede grass extracts or fractions thereof as active ingredients[2017-05-23]

연구과제 수행 실적

오믹스기반 쌍자엽식물의 방사선 반응 연구 종특이성 방사선 회복시스템 규명 및 활용 연구