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김래권 교수

Raekwon Kim

INFO

  • 소속캠퍼스한국원자력연구원
  • 전공 방사선 과학기술
  • 연락처042-868-8967
  • 출신전공생명과학과
  • 학위박사
  • 최종출신대학한양대학교
  • 이메일

연구분야

암줄기세포, 분자생화학, 방사선생물학

Cancer stem cells, Molecular biochemistry, Radiobiology

대표연구실적

-  Rae-Kwon Kim, Yongjoon Suh, Eunji Hwang, Ki-Chun Yoo, Kyu-Sil Choi, Sungkwan An, Sang-Gu Hwang, In Gyu Kim, Min-Jung Kim and Su-Jae Lee./PKCδ maintains phenotypes of tumor initiating cells through cytokine-mediated autocrine loop with positive feedback/Oncogene/2015.11.12 -  Rae-Kwon Kim, Neha Kaushik, Yongjoon Suh, Ki-Chun Yoo, Yan-Hong Cui, Min-Jung Kim, Hae-June Lee, In-Gyu Kim, Su-Jae Lee./Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer/Oncotarget/2016.08.16 -  Rae-Kwon Kim, Min-Jung Kim, Ki-Moon Seong, Neha Kaushik, Yongjoon Suh, Ki-Chun Yoo, Yan-Hong Cui, Seon-Young Nam, Young-Woo Jin, Su-Jae Lee./Beneficial effects of low dose radiation in response to the oncogenic K-ras induced cellular transformation/Scientific Reports/2015.10.30

저서(최근 5년)

-  Separation and capture of circulating tumor cells from whole blood using a bypass integrated microfluidic trap array[2014-08-01]

논문(최근 5년)

-  Novel signaling axis for ROS generation during K-Ras-induced cellular transformation[ CELL DEATH AND DIFFERENTIATION,2014-08-21] -  Functional characterization of P-glycoprotein in the intertidal copepod Tigriopus japonicus and its potential role in remediating metal pollution[ AQUATIC TOXICOLOGY,2014-09-01] -  Doxycycline Enhances Survival and Self-Renewal of Human Pluripotent Stem Cells[ STEM CELL REPORTS,2014-08-12] -  Activation of KRAS promotes the mesenchymal features of basal type breast cancer[ EXPERIMENTAL AND MOLECULAR MEDICINE,2015-01-30] -  Phloroglucinol suppresses metastatic ability of breast cancer cells by inhibition of epithelial-mesenchymal cell transition[ CANCER SCIENCE,2015-01-01] -  Radiation promotes malignant phenotypes through SRC in breast cancer cells[ CANCER SCIENCE,2015-01-01] -  Persistent activation of STAT3 by PIM2-driven positive feedback loop for epithelial-mesenchymal transition in breast cancer[ CANCER SCIENCE,2015-06-01] -  Novel anticancer activity of phloroglucinol against breast cancer stem-like cells[ TOXICOLOGY AND APPLIED PHARMACOLOGY,2015-08-01] -  Beneficial effects of low dose radiation in response to the oncogenic K-ras induced cellular transformation[ SCIENTIFIC REPORTS,2015-10-30] -  PKCδ maintains phenotypes of tumor initiating cells through cytokine-mediated autocrine loop with positive feedback[ ONCOGENE,2015-11-12] -  ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-catenin[ ONCOGENE,2015-12-10] -  NADPH Oxidase 1 Activity and ROS Generation Are Regulated by Grb2/Cbl-Mediated Proteasomal Degradation of NoxO1 in Colon Cancer Cells[ CANCER RESEARCH,2016-02-15] -  Effects of multi-walled carbon nanotube (MWCNT) on antioxidant depletion, the ERK signaling pathway, and copper bioavailability in the copepod (Tigriopus japonicus)[ AQUATIC TOXICOLOGY,2016-02-01] -  PKCδ Activated by c-MET Enhances Infiltration of Human Glioblastoma Cells through NOTCH2 Signaling[ ONCOTARGET,2015-03-07] -  Clogging-free microfluidics for continuous size-based separation of microparticles[ SCIENTIFIC REPORTS,2016-05-01] -  Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer[ ONCOTARGETS AND THERAPY,2016-08-16] -  Low-dose radiation decreases tumor progression via the inhibition of the JAK1/STAT3 signaling axis in breast cancer cell lines[ SCIENTIFIC REPORTS,2017-02-27] -  PRMT8 Controls the Pluripotency and Mesodermal Fate of Human Embryonic Stem Cells By Enhancing the PI3K/AKT/SOX2 Axis[ STEM CELLS,2017-09-01]

특허(최근 5년)

-  K-Ras 과발현된 암 세포의 이동 및 침윤 억제[2016-02-05] -  엑콜 화합물을 함유하는, K-라스 발현 암에 대한 항암용 조성물[2016-02-17] -  뇌암의 침윤 및 이동 억제용 약제학적 조성물[2016-04-12] -  저선량 방사선을 이용한 암화유전자 RAS-유도 악성 암화 억제[2016-08-23] -  저선량 방사선 조사에 의한 암화 예방 방법[2016-08-23]