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윤석주 교수

Yoon Seok Joo

INFO

  • 소속캠퍼스안전성평가연구소
  • 전공 인체 및 환경 독성학
  • 직급캠퍼스대표교수
  • 연락처042-610-8330
  • 출신전공수의학
  • 학위박사
  • 최종출신대학Hokkaido University
  • 이메일

연구분야

간독성, 분자독성, 독성유전체학

Hepatotoxicity, molecular toxicology, toxicogenomics

대표연구실적

-  1) Kim D.G., Oh J.H., Lee E.H., Lee J.H., Park H.J., Kwon M.S. and S. Yoon. 2010 The stoichiometric relationship between KCNH-2 and KCNE-2 in IKr channel formation. Intl. J. Cardiology, 145(2): 272-274. -  2) Heo S.H., Oh J.H., Park H.J., Kwon M.S. Suresh VS Rana and S. Yoon. 2010. Toxicoproteomic Analysis of Phalloidin-induced Cholestasis in Mouse Liver. Mol. & Cell. Toxicol., 6(1):87-95. -  3) Lee Y.S., Oh J.H., Yoon S., Song C.W., Kwon M.S., Kim K.H., Cho M.J., Mollah M.L., Kim Y.D., Kim C.D., and Lee J.H. 2010. Differential gene expression profiles of radioresistant non-small cell lung cancer cell lines established by fractionated irradiation: Tumor protein p53 inducible protein 3 confers sensitivity to ionizing radiation. Int J Radiat Oncol Biol Phys., 77(3): 858-866.

논문(최근 5년)

-  Cytochrome P450 system expression and DNA adduct formation in the liver of Zacco[environ Toxicol,2014-09-01] -  Genomic and proteomic analyses of 1,3-dinitrobenzene-induced testicular toxicity in Sprague-Dawley rats[Reprod toxicol,2013-10-06] -  Nonylphenol-induced apoptotic cell death in mouse TM4 Sertoli cells via the generation of reactive oxygen species and activation of the ERK signaling pathway[Journal of applied toxicology,2013-05-13] -  Comparative Gene Expression Analysis in the Liver, Kidney and Blood Vessels during Renal Injury after Repeated Exposure to Tacrolimus in Sprague-Dawley Rats[BioChip Journal,2015-08-07] -  Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes[ PLOS ONE,2015-07-15] -  Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice[ ONCOTARGET,2016-02-25] -  RNA-Seq analysis reveals new evidence for inflammationrelatedchanges in aged kidney[ ONCOTARGET,2016-05-03] -  Integrative analysis of genes and miRNAs alterations in human embryonic stem cells-derived neural cells after exposure to silver nanoparticles[ TOXICOLOGY AND APPLIED PHARMACOLOGY,2015-11-06] -  Analysis of genomic responses in a rat lung model treated with a humidifier sterilizer containing polyhexamethyleneguanidine phosphate[ TOXICOLOGY LETTERS,2016-12-15] -  Developmental Toxicity of Zinc Oxide Nanoparticles to Zebrafish (Danio rerio): A Transcriptomic Analysis[ PLOS ONE,2016-08-09] -  Xeno-sensing activity of the aryl hydrocarbon receptor in human pluripotent stem cell-derived hepatocyte-like cells[ SCIENTIFIC REPORTS,2016-02-22] -  A gene expression approach in zebraifsh (Danio rerio) embryo for predicting early life stage toxicity from expose to ZnO nanoparticles and ZnSO4[Molecular & Cellular Toxicology,2016-10-16] -  The pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury[ ONCOTARGET,2017-07-31] -  Physiological Effects of Ac4ManNAz and Optimization of Metabolic Labeling for Cell Tracking[ THERANOSTICS,2017-03-01] -  Comparative study of active and inactive hepatocarcinogens using a QSAR-based prediction model[Molecular and Cellular Toxicology,2013-12-01]

특허(최근 5년)

-  간내담즙 정체 진단용 바이오마커 및 이를 이용한 간내 담즙 정체 진단방법[2014-04-01] -  내분비 장애물질에 의해 유도된 생식독성을 이용한 생식독성물질 검출용 키트 및 이를 이용한 검출 방법[2014-01-15] -  노닐페놀에 의해 유도된 생식계 독성을 이용한 노닐페놀 노출 여부 확인용 miRNA 마이크로어레이 키트 및 이의 검출 방법[2013-08-05] -  나노물질에 의한 신경독성을 확인하기 위한 바이오마커 및 이를 이용한 신경돇어 확인방법[2017-06-01] -  비알콜성 지방간암(NAFLD) 치료 및 진단용 암줄기세포 바이오마커[2015-10-28]