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이규홍 교수

Lee Kyuhong

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  • 소속캠퍼스안전성평가연구소
  • 전공 인체 및 환경 독성학
  • 연락처063-570-8111
  • 출신전공고체물리학
  • 학위박사
  • 최종출신대학건국대학교
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연구분야

흡입독성연구, 만성호흡기질환

Inhalation Toxicity Research, Chronic Respiratory Disease

대표연구실적

-  Humidifier disinfectant-associated interstitial lung disease in an animal model induced by polyhexamethylene guanidine aerosol. Am J Respir Crit Care Med. 2014 -  Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis. J Biol Chem. 2016 -  Mainstream cigarette smoke accelerates the progression of nonalcoholic steatohepatitis by modulating Kupffer cell-mediated hepatocellular apoptosis in adolescent mice. Toxicol Lett. 2016

논문(최근 5년)

-  Oxidative stress induced by cigarette smoke extracts in human brain cells (T98G) and human brain microvascular endothelial cells (HBMEC) in mono and co-culture[ JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES,2015-11-08] -  Is every inhalant safe?[ AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE,2015-01-01] -  Evaluation of toxicity to triclosan in rats following 28 days of exposure to aerosol inhalation[Regulatory Toxicology and Pharmacology,2015-03-01] -  MicroRNA response of inhalation exposure to hexanal in lung tissues from fischer 344 rats[ ENVIRONMENTAL TOXICOLOGY,2015-09-14] -  Acute high level toluene exposure decreases hippocampal neurogenesis in rat[ TOXICOLOGY AND INDUSTRIAL HEALTH,2015-10-16] -  Chronic pulmonary accumulation of iron exid nanoparticles induced Th-1 type immune response stimulating the function of antigen presenting cells[ ENVIRONMENTAL RESEARCH,2015-11-01] -  A gloval initiative to refine acute inhalation studies through the use of evident toxicity as an endpoint[ REGULATORY TOXICOLOGY AND PHARMACOLOGY,2015-12-01] -  short term manganese inhalation decreases brain dopamine transporter levels without disrupting motor skills in rats[ JOURNAL OF TOXICOLOGICAL SCIENCES,2016-01-01] -  Manganese enhanced MR imaging of brain activation evoked by noxious peripheral electrical stimulation [ NEUROSCIENCE LETTERS,2016-02-01] -  polyhexamethylene guanidine phosphate aerosol particles induce pulmonary inflammation and fibrotic responses[ ARCHIVES OF TOXICOLOGY,2016-03-01] -  self assembled micelle interfering RNA for effective and safe targeting of dysregulated Genes in pulmonary fibrosis[ JOURNAL OF BIOLOGICAL CHEMISTRY,2016-04-18] -  Establishment of a mouse model for pulmonary inflammation and fibrosis by intratracheal instillation of polyhexametaheneguanidine phosphate[ JOURNAL OF TOXICOLOGIC PATHOLOGY,2016-04-01] -  Mainstream cigarette smoke accelerates thhe progression of nonalcoholic steatohepatits by modulating Kupffer cell mediated hepatocellular apoptosis in adolescent mice[ TOXICOLOGY LETTERS,2016-08-01] -  Cigarette smoking condensate disrupts endoplasmic reticulum-golgi network homeostasis through GOLPH3 expression in normal lung epithelial cells[ NICOTINE & TOBACCO RESEARCH,2016-09-01] -  differential effect between cigarette total particulate matter and cigarette smoke extract on blood and blood vessel[Toxicological Research,2016-10-01] -  Evaluating the influence of side stream cigarette smoke at an early stage of non alcoholic steatohepatitis progression in mice[Toxicological Research,2017-01-01] -  NADPH oxidase mediates cigarette smoke-induced superoxide generation in rat vascular smooth muscle cells[ TOXICOLOGY IN VITRO,2017-02-01] -  Toxicogenomic analysis of the pulmonary toxic effects of hexanal in F344 rat[ ENVIRONMENTAL TOXICOLOGY,2017-02-01] -  Cigarette smoke extracts induced the colon cancer migration via regulating epithelial mesenchymal transition and metastatic genes in human colon cancer cells[ ENVIRONMENTAL TOXICOLOGY,2017-02-01] -  Pulmonary glass particles may persist in the lung suppressing function of immune cells[ ENVIRONMENTAL TOXICOLOGY,2017-02-01] -  Analysis of genomic responses in a rat lung model treated with a humidifier sterilizer containing PHMG[ TOXICOLOGY LETTERS,2017-02-01] -  Pulmonary persistence of graphene nanoplatelets may disturb physiological and immunological homeostasis [ JOURNAL OF APPLIED TOXICOLOGY,2017-03-01] -  Effect of cigarette smoke extracts [ REPRODUCTIVE TOXICOLOGY,2017-10-01]