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이종화 교수

JONG-HWA LEE

INFO

  • 소속캠퍼스안전성평가연구소
  • 연락처042-610-8092
  • 출신전공약제과학
  • 학위박사
  • 최종출신대학서울대학교
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연구분야

독성동태, 약물동태, 생체시료분석, 약물대사

Toxico-/Pharmacokinetics, Bioanalysis, Drug metabolism

대표연구실적

-  Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats -  Gender Differences in the Hepatic Elimination and Pharmacokinetics of Lobeglitazone in Rats -  A novel HPLC?MS/MS method for the simultaneous determination of astemizole and its major metabolite in dog or monkey plasma and application to pharmacokinetics

논문(최근 5년)

-  A 14-Day Repeated Dose Toxicity of Epimedii Herba Aqueous Extract Administered by Oral Gavage in F344 Rats[생약학회지,2014-11-18] -  A novel HPLC?MS/MS method for the simultaneous determination of astemizole and its major metabolite in dog or monkey plasma and application to pharmacokinetics[ JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2015-05-21] -  The identification of lobeglitazone metabolites in rat liver microsomes and the kinetics of the in vivo formation of the major metabolite M1 in rats[ JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2015-07-30] -  Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats[ JOURNAL OF PHARMACEUTICAL SCIENCES,2015-02-03] -  Gender Differences in the Hepatic Elimination and Pharmacokinetics of Lobeglitazone in Rats[ BIOPHARMACEUTICS & DRUG DISPOSITION,2015-05-15] -  Development of QTc prolongation model incorporating circadian rhythm using harmonic model[ XENOBIOTICA,2014-12-05] -  Quantification of zabofloxacin in rat plasma using HPLC-UV detector and its application to a Pharmacokinetic study[ JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES,2014-01-01] -  1'-Acetoxychavicol Acetate Isolated from Alpinia galanga Ameliorates Ovalbumin-Induced Asthma in Mice[PLOS ONE,2013-02-25] -  Self-microemulsifying drug-delivery system for improved oral bioavailability of pranlukast hemihydrate: preparation and evaluation[INTERNATIONAL JOURNAL OF NANOMEDICINE,2013-01-04] -  Evaluation of the Antioxidant Activity and Physiological Functionality of Baegilju[한국미생물·생명공학회지,2013-12-18] -  Embryotoxicity and Toxicokinetics of the Antimalarial Artesunate in Rats[한국독성학회지,2013-01-24] -  Milk Transfer and Toxicokinetics of Valproic Acid in Lactating Cynomolgus Monkeys[한국독성학회지,2013-03-26]