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문경식 교수

Moon, Kyoung-Sik

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  • 소속캠퍼스안전성평가연구소
  • 전공 인체 및 환경 독성학
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연구분야

바이오의약품, 화학물질등에 대한 안전성연구

Safety evaluation on biologics and chemicals

대표연구실적

-  Twenty-six week oral carcinogenicity study of 3-monochloropropane-1,2-diol in CB6F1rasH2 transgenic mice -  CKD-501, a novel selective PPARγ agonist,shows no carcinogenic potential in ICR mice following oral administration for 104 weeks -  Safety assessment of freeze-dried powdered Tenebrio molitor larvae (yellow mealworm) as novel food source: Evaluation of 90-day toxicity in Sprague-Dawley rats

논문(최근 5년)

-  Evaluation of Genotoxicity and 28-day Oral Dose Toxicity on Freeze-dried[Toxicological Research,2014-06-01] -  Preclinical Safety Evaluation of Intravenously Administered SAL200[ ANTIMICROBIAL AGENTS AND CHEMOTHERAPY,2014-04-01] -  Subchronic Oral Dose Toxicity of Freeze-dried Powder[Toxicological Research,2015-03-01] -  Increased serum bile acid concentration following low-dose chronic[ TOXICOLOGY AND APPLIED PHARMACOLOGY,2015-07-01] -  Comparative Gene Expression Analysis in the Liver, Kidney and[BIOCHIP JOURNAL,2015-08-01] -  A 28-day oral gavage toxicity study of 3-monochloropropane-1,2-diol[ FOOD AND CHEMICAL TOXICOLOGY,2015-10-01] -  Toxicological evaluation of genotoxicity and 28-day oral toxicity study on[JOURNAL OF ASIA-PACIFIC ENTOMOLOGY,2015-10-01] -  Characterization of urinary metabolites as biomarkers of[ TOXICOLOGY LETTERS,2016-03-01] -  Safety assessment of freeze-dried powdered Tenebrio molitor larvae[ REGULATORY TOXICOLOGY AND PHARMACOLOGY,2016-03-01] -  Twenty?six?week oral carcinogenicity study[ARCHIVES OF TOXICOLOGY,2016-03-01] -  Tumorigenicity Evaluation of Umbilical Cord Blood-derived[Toxicological Research,2016-07-01] -  Subacute toxicity evaluation of KR-33493, FAF1 inhibitor for a new anti-parkinson's disease agent, after oral administration in rats and dogs[REGULATORY TOXICOLOGY AND PHARMACOLOGY,2016-09-22] -  Analysis and Stability Test of the Extracts from Astragali Radix, Paeoniae Radix, and Corni Fructus for Toxicity Study[생약학회지,2017-01-02] -  Potential urinary biomarkers of nephrotoxicity in cyclophosphamide-treated rats investigated by NMR-based metabolic profiling[JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY,2017-02-01] -  Subchronic oral toxicity study of Korean red ginseng extract in Sprague-Dawley rats with a 4-week recovery period[REGULATORY TOXICOLOGY AND PHARMACOLOGY,2017-11-01] -  Toxicological safety evaluation of freeze-dried Protaetia brevitarsis larva powder[Toxicology Reports,2018-06-01] -  Identification and characterization of amiodarone metabolites in rats using UPLC?ESI-QTOFMS-based untargeted metabolomics approach[JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES,2018-04-11] -  Therapeutic effect of a xeno-free three-dimensional stem cell mass in a hind limb ischemia model[TISSUE ENGINEERING PART A,2018-09-14]

연구과제 수행 실적

혈관화된 3차원 생체조직 (간/심장, 암) 모사 칩 기반 약물 효능 및 독성 평가 시스템의 개발 중간엽 줄기세포 유래 엑소좀의 품질평가 및 안전성 평가 기술개발 안구내 주사용 AAV 치료제 독성시험 EGFR 길항제의 동반진단 바이오마커 및 검증 시스템 개발 CAR-NK 유전자치료제의 비임상독성평가